Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.56 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL37463 | 0.83 | IDO1 (0.70) | IDO1AKR1C3ALDH1A1LOXL2MAOB | |
| Dimethylamine SCHEMBL7859839 | 0.83 | IDO1 (0.56) | IDO1AKR1C3ALDH1A1LOXL2RECQL | |
| SCHEMBL28888040 | 0.81 | TSHR (0.53) | ALDH1A1MAOBTSHRMAPTMEN1 | |
| SCHEMBL7087223 | 0.80 | IDO1 (0.61) | IDO1AKR1C3ALDH1A1LOXL2HSD17B10 | |
| SCHEMBL6395926 | 0.80 | IDO1 (0.53) | IDO1AKR1C3LOXL2MAOBPOLB | |
| SCHEMBL14042050 | 0.79 | IDO1 (0.59) | IDO1AKR1C3ALDH1A1LOXL2RECQL | |
| SCHEMBL6141174 | 0.78 | IDO1 (0.63) | IDO1AKR1C3ALDH1A1LOXL2MAOB | |
| SCHEMBL629644 | 0.78 | IDO1 (0.63) | IDO1AKR1C3ALDH1A1LOXL2MAOB | |
| SCHEMBL12528314 | 0.78 | IDO1 (0.50) | IDO1AKR1C3ALDH1A1MAOB | |
| SCHEMBL15114767 | 0.77 | IDO1 (0.58) | IDO1AKR1C3ALDH1A1LOXL2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110669058-A | Tricyclic quinolone carboxylic acid and preparation method thereof | 江西农业大学 | 2020-01-10 | — | — | CN | claimed |
| CN-110669058-A | Tricyclic quinolone carboxylic acid and preparation method thereof | 江西农业大学 | 2020-01-10 | — | — | CN | disclosed |