Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.70 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.61 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | CA7 | P43166 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11441117 | 0.92 | IDO1 (0.61) | IDO1AKR1C3LOXL2TSHRCYP2C19 | |
| SCHEMBL19621588 | 0.92 | IDO1 (0.61) | IDO1AKR1C3LOXL2TSHRCYP2C19 | |
| SCHEMBL9347010 | 0.90 | IDO1 (0.59) | IDO1AKR1C3LOXL2TSHRCA12 | |
| SCHEMBL6141174 | 0.90 | IDO1 (0.63) | IDO1AKR1C3LOXL2TSHRCA12 | |
| SCHEMBL629644 | 0.90 | IDO1 (0.63) | IDO1AKR1C3LOXL2TSHRCA12 | |
| SCHEMBL27712803 | 0.90 | TSHR (0.60) | IDO1AKR1C3TSHRCYP2C19ALDH1A1 | |
| SCHEMBL7027123 | 0.88 | IDO1 (0.61) | IDO1AKR1C3LOXL2TSHRCA12 | |
| SCHEMBL7087223 | 0.88 | IDO1 (0.61) | IDO1AKR1C3LOXL2TSHRCA12 | |
| SCHEMBL7032223 | 0.88 | IDO1 (0.61) | IDO1AKR1C3LOXL2TSHRCA12 | |
| SCHEMBL3935764 | 0.88 | IDO1 (0.61) | IDO1AKR1C3LOXL2TSHRCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 311 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112812027-B | Methoxyaniline compound and synthetic method thereof | 湘潭大学 | 2022-05-27 | — | — | CN | claimed |
| CN-114411169-A | Photoelectrocatalysis hydrogen production and nitro aromatic hydrocarbon in-situ hydrogenation integrated device and application | 山西大学 | 2022-04-29 | — | — | CN | claimed |
| WO-2021216722-A1 | STEREOSELECTIVE PROCESS OF MANUFACTURE OF PURINE PHOSPHORAMIDATES | Atea Pharmaceuticals, Inc. (US) | 2021-10-28 | — | — | WO | claimed |
| CN-112812027-A | Methoxyaniline compound and synthetic method thereof | 湘潭大学 | 2021-05-18 | — | — | CN | claimed |
| EP-2635547-A1 | CHIRAL INTERMEDIATES USEFUL FOR THE PREPARATION OF HYDROXYPHOSPHINE LIGANDS | United Phosphorus Limited (IN) | 2013-09-11 | — | — | EP | claimed |
| US-20130217900-A1 | CHIRAL INTERMEDIATES USEFUL FOR THE PREPARATION OF HYDROXYPHOSPHINE LIGANDS | UNITED PHOSPHORUS LIMITED (IN) | 2013-08-22 | — | — | US | claimed |
| WO-2012059807-A1 | CHIRAL INTERMEDIATES USEFUL FOR THE PREPARATION OF HYDROXYPHOSPHINE LIGANDS | UNITED PHOSPHORUS LIMITED (IN) | 2012-05-10 | — | — | WO | claimed |
| US-7166723-B2 | Process for the synthesis of derivatives of 2,3-dihydro-1,4-dioxino-[2,3-f] quinoline | WYETH (US) | 2007-01-23 | — | — | US | claimed |
| US-20060074240-A1 | Process for the synthesis of derivatives of 2,3-dihydro-1,4-dioxino-[2,3-f] quinoline | WYETH (US) | 2006-04-06 | — | — | US | claimed |
| CN-1247590-C | Process for synthesis of derivatives of 2,30dihydro-1,4-dioxino-[2,3-f]quinoline | WYETH CORP (US) | 2006-03-29 | — | — | CN | claimed |
| WO-2005058246-A2 | METHOD FOR PREPARING RADIOLABELED THYMIDINE | MOLECULAR TECHNOLOGIES, INC. (US) | 2005-06-30 | — | — | WO | claimed |
| US-20050131224-A1 | Method for preparing radiolabeled thymidine | CTI PET SYSTEMS, INC. | 2005-06-16 | — | — | US | claimed |
| US-20040186123-A1 | Process for the synthesis of derivatives of 2, 3-dihydro-1, 4-dioxino- [2, 3-f] quinoline | WYETH | 2004-09-23 | — | — | US | claimed |
| CN-1509290-A | Process for synthesis of derivatives of 2,30dihydro-1,4-dioxino-[2,3-f]quinoline | — | 2004-06-30 | — | — | CN | claimed |
| EP-1387845-A2 | PROCESSES FOR THE SYNTHESIS OF DERIVATIVES OF 2,3-DIHYDRO-1,4-DIOXINO-(2,3-f) QUINOLINE | Wyeth (US) | 2004-02-11 | — | — | EP | claimed |
| US-20030215871-A1 | Chemically inert molecular tags | PHARMACOPEIA, INC. (US) | 2003-11-20 | — | — | US | claimed |
| US-20020187983-A1 | Process for the synthesis of derivatives of 2, 3-dihydro-1, 4-dioxino- [2, 3-f] quinoline | WYETH | 2002-12-12 | — | — | US | claimed |
| WO-2002092602-A2 | PROCESSES FOR THE SYNTHESIS OF DERIVATIVES OF 2,3-DIHYDRO-1,4-DIOXINO-[2,3-f] QUINOLINE | WYETH (US) | 2002-11-21 | — | — | WO | claimed |
| EP-0766660-B1 | CYCLOHEXANONE DERIVATIVES, METHOD OF PREPARING THEM AND INTERMEDIATES USED IN THE METHOD | SCHERING AG (DE) | 1999-12-29 | — | — | EP | claimed |
| US-5886233-A | Cyclohexanone derivatives, process for their production and intermediate products of the process | SCHERING AKTIENGESELLSCHAFT (DE) | 1999-03-23 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060074240-A1 | Process for the synthesis of derivatives of 2,3-dihydro-1,4-dioxino-[2,3-f] quinoline | CYP1A1, CYP2F1, CYP1A2 | IDO1 375/4885AKR1C3 600/4885LOXL2 2250/4885 |
| US-20030215871-A1 | Chemically inert molecular tags | ALK, ADH1A, ADH1C | IDO1 4235/4885AKR1C3 180/4885LOXL2 2848/4885 |
| US-20130217900-A1 | CHIRAL INTERMEDIATES USEFUL FOR THE PREPARATION OF HYDROXYPHOSPHINE LIGANDS | CYP21A2, HRH3, P4HA1 | IDO1 355/4885AKR1C3 109/4885LOXL2 3014/4885 |
| US-20020187983-A1 | Process for the synthesis of derivatives of 2, 3-dihydro-1, 4-dioxino- [2, 3-f] quinoline | CYP1A1, CYP2F1, CYP1B1 | IDO1 317/4885AKR1C3 604/4885LOXL2 2215/4885 |
| US-20050131224-A1 | Method for preparing radiolabeled thymidine | TYMP, TYMS, DUT | IDO1 912/4885AKR1C3 541/4885LOXL2 3707/4885 |
| US-20040186123-A1 | Process for the synthesis of derivatives of 2, 3-dihydro-1, 4-dioxino- [2, 3-f] quinoline | CYP1A1, CYP2F1, CYP1B1 | IDO1 317/4885AKR1C3 604/4885LOXL2 2215/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.