Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 9/20 | 0.53 |
| ▸ | FNTA | P49354 | 1/20 | 0.41 |
| ▸ | FNTB | P49356 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP3 | P08254 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CTSA | P10619 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | XDH | P47989 | 3/20 | 0.35 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.35 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | BLVRB | P30043 | 1/20 | 0.35 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28388152 | 0.83 | SLC22A12 (0.47) | SLC22A12FNTAFNTBMMP2MMP3 | |
| SCHEMBL28384734 | 0.82 | SLC22A12 (0.62) | SLC22A12FNTAFNTBMAPTKDM4E | |
| SCHEMBL28384719 | 0.82 | SLC22A12 (0.49) | SLC22A12FNTAFNTBMMP2MMP3 | |
| SCHEMBL17899874 | 0.80 | SLC22A12 (0.54) | SLC22A12FNTAFNTBKDM4EALDH1A1 | |
| SCHEMBL28388187 | 0.76 | MMP2 (0.40) | FNTAFNTBMMP2MMP3LMNA | |
| SCHEMBL17899900 | 0.74 | SLC22A12 (0.58) | SLC22A12 | |
| SCHEMBL17899840 | 0.73 | SLC22A12 (0.68) | SLC22A12FNTAFNTB | |
| SCHEMBL23129684 | 0.72 | SLC22A12 (0.53) | SLC22A12 | |
| SCHEMBL28386340 | 0.72 | SLC22A12 (0.48) | SLC22A12FNTAFNTBMAPTKDM4E | |
| SCHEMBL28387543 | 0.71 | SLC22A12 (0.48) | SLC22A12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107108478-B | URAT1 inhibitors | 日本化学药品株式会社 | 2020-04-24 | — | — | CN | disclosed |