Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK3 | P52333 | 3/20 | 0.37 |
| ▸ | EGFR | P00533 | 3/20 | 0.37 |
| ▸ | BTK | Q06187 | 1/20 | 0.37 |
| ▸ | ITK | Q08881 | 1/20 | 0.37 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.34 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28385472 | 0.92 | BTK (0.42) | JAK3EGFRBTKITKPDGFRA | |
| SCHEMBL28388723 | 0.91 | FGFR1 (0.41) | JAK3EGFRBTKITKFGFR1 | |
| SCHEMBL28385548 | 0.91 | BTK (0.38) | JAK3EGFRBTKITKFGFR1 | |
| SCHEMBL28383333 | 0.91 | JAK3 (0.39) | JAK3EGFRBTKITK | |
| SCHEMBL28388017 | 0.88 | — | — | |
| SCHEMBL28387169 | 0.87 | — | — | |
| SCHEMBL28382401 | 0.87 | FGFR1 (0.42) | JAK3EGFRBTKITKFGFR1 | |
| SCHEMBL28387958 | 0.84 | EGFR (0.42) | JAK3EGFRBTKITKPDGFRA | |
| SCHEMBL28387194 | 0.82 | FGFR1 (0.45) | EGFRBTKITKFGFR1KDR | |
| SCHEMBL28383465 | 0.82 | BTK (0.42) | JAK3EGFRBTKFGFR1KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105682661-B | Certain chemical entities, compositions, and methods | 润新生物公司 | 2020-03-27 | — | — | CN | claimed |
| CN-109851617-B | Chemical entities, compositions, and methods | 润新生物公司 | 2022-08-16 | — | — | CN | disclosed |
| CN-111285813-A | Chemical entities, compositions, and methods | 润新生物公司 | 2020-06-16 | — | — | CN | disclosed |
| CN-105682661-B | Certain chemical entities, compositions, and methods | 润新生物公司 | 2020-03-27 | — | — | CN | disclosed |