Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27821224 | 0.82 | — | — | |
| SCHEMBL27580035 | 0.82 | — | — | |
| SCHEMBL28453747 | 0.82 | F12 (0.43) | — | |
| SCHEMBL27576211 | 0.77 | ATM (0.31) | — | |
| SCHEMBL23846923 | 0.76 | OPRL1 (0.32) | OPRL1 | |
| SCHEMBL26503989 | 0.76 | HTR2A (0.36) | OPRL1 | |
| SCHEMBL28457172 | 0.75 | MAPT (0.41) | MEN1KMT2A | |
| SCHEMBL28460793 | 0.72 | F12 (0.40) | — | |
| SCHEMBL28384647 | 0.70 | — | — | |
| SCHEMBL23846917 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109503478-B | 2, 3-dihydro-1H-quinoline-4-ketone thiosemicarbazone derivative and preparation method and application thereof | 岭南师范学院 | 2020-04-24 | — | — | CN | disclosed |