Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 7/20 | 0.51 |
| ▸ | MMP3 | P08254 | 3/20 | 0.39 |
| ▸ | FNTA | P49354 | 2/20 | 0.35 |
| ▸ | FNTB | P49356 | 2/20 | 0.35 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.35 |
| ▸ | CTSS | P25774 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.33 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19435501 | 0.79 | SLC22A12 (0.55) | SLC22A12MMP3CA1CA2GPR119 | |
| SCHEMBL28388165 | 0.77 | SLC22A12 (0.40) | SLC22A12FNTAFNTBGPR119 | |
| SCHEMBL19453076 | 0.76 | SLC22A12 (0.55) | SLC22A12MMP3CTSSCTSKCA1 | |
| SCHEMBL17899858 | 0.75 | SLC22A12 (0.74) | SLC22A12MMP3CA1CA2GPR119 | |
| SCHEMBL17899876 | 0.73 | SLC22A12 (0.67) | SLC22A12 | |
| SCHEMBL29441758 | 0.73 | SLC22A12 (0.67) | SLC22A12 | |
| SCHEMBL28387584 | 0.73 | ELANE (0.40) | SLC22A12MMP3FNTAFNTBMMP2 | |
| SCHEMBL28386412 | 0.73 | SLC22A12 (0.44) | SLC22A12FNTAFNTB | |
| SCHEMBL28383766 | 0.73 | SLC22A12 (0.63) | SLC22A12FNTAFNTB | |
| SCHEMBL23129626 | 0.72 | SLC22A12 (0.57) | SLC22A12MMP3CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107108478-B | URAT1 inhibitors | 日本化学药品株式会社 | 2020-04-24 | — | — | CN | disclosed |