SCHEMBL19453076

SCHEMBL19453076

CC(C)(C)OC(=O)/C=C/Sc1ccc2ccccc2c1-c1ccc(C#N)cc1

nearest known ligand 0.55

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ SLC22A12 Q96S37 11/20 0.55
▸ MMP3 P08254 2/20 0.36
▸ CA1 P00915 1/20 0.34
▸ CA2 P00918 1/20 0.34
▸ GPR119 Q8TDV5 1/20 0.33
▸ EGLN2 Q96KS0 2/20 0.32
▸ CYP19A1 P11511 1/20 0.32
▸ CTSS P25774 1/20 0.32
▸ CTSK P43235 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17899872 0.84 SLC22A12 (0.65) SLC22A12MMP3CA1CA2CYP19A1
SCHEMBL17899858 0.83 SLC22A12 (0.74) SLC22A12MMP3CA1CA2GPR119
SCHEMBL19453071 0.80 SLC22A12 (0.46) SLC22A12MMP3CA1CA2GPR119
SCHEMBL28385860 0.80 SLC22A12 (0.46) SLC22A12MMP3CA1CA2GPR119
SCHEMBL19435501 0.80 SLC22A12 (0.55) SLC22A12MMP3CA1CA2GPR119
SCHEMBL28387537 0.76 SLC22A12 (0.51) SLC22A12MMP3CA1CA2GPR119
SCHEMBL17899876 0.75 SLC22A12 (0.67) SLC22A12
SCHEMBL29441758 0.75 SLC22A12 (0.67) SLC22A12
SCHEMBL23129626 0.74 SLC22A12 (0.57) SLC22A12MMP3CA1CA2CYP19A1
SCHEMBL28387514 0.71 SLC22A12 (0.67) SLC22A12MMP3CA1CA2CYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3241822-B1 URAT1 INHIBITOR NIPPON CHEMIPHAR CO (JP) 2021-03-24 — — EP claimed
CN-107108478-B URAT1 inhibitors 日本化学药品株式会社 2020-04-24 — — CN disclosed
US-20170290795-A1 URAT1 INHIBITOR J-PHARMA CO., LTD. (JP) 2017-10-12 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170290795-A1 URAT1 INHIBITOR SLC10A1, XDH, URB2 SLC22A12 512/4885MMP3 2867/4885CA1 1332/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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