Oxirane

Oxirane

SCHEMBL2838796

C1CO1.C=CC(=O)Oc1ccccc1

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 4/20 0.50
ATM Q13315 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
KMT2A Q03164 5/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
KDM4E B2RXH2 1/20 0.41
NPC1 O15118 1/20 0.41
RAB9A P51151 1/20 0.41
TGM2 P21980 1/20 0.41
AKT1 P31749 1/20 0.41
PDE6D O43924 1/20 0.40
MEN1 O00255 1/20 0.40
CASP3 P42574 1/20 0.40
SENP7 Q9BQF6 1/20 0.40
HSD17B10 Q99714 2/20 0.39
HPGD P15428 1/20 0.39
ALOX15 P16050 1/20 0.39
EPHX1 P07099 1/20 0.39
THRA P10827 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28916 0.90 THRB (0.58) THRBATMTDP1L3MBTL1KMT2A
Hydrogen Peroxide SCHEMBL28479331 0.90 THRB (0.58) THRBATMTDP1L3MBTL1KMT2A
Potassium SCHEMBL30641492 0.88 THRB (0.56) THRBATMTDP1L3MBTL1KMT2A
Ethylene SCHEMBL28842231 0.88 THRB (0.56) THRBATMTDP1L3MBTL1KMT2A
SCHEMBL28429842 0.88 THRB (0.56) THRBATMTDP1L3MBTL1KMT2A
SCHEMBL28968163 0.88 THRB (0.56) THRBATMTDP1L3MBTL1KMT2A
SCHEMBL30209195 0.88 THRB (0.56) THRBATMTDP1L3MBTL1KMT2A
SCHEMBL11576296 0.88 THRB (0.56) THRBATMTDP1L3MBTL1KMT2A
SCHEMBL10479978 0.88 THRB (0.56) THRBATMTDP1L3MBTL1KMT2A
SCHEMBL30350971 0.88 THRB (0.56) THRBATMTDP1L3MBTL1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8192898-B2 Composition for fluorine-containing volume holographic data recording material and fluorine-containing volume holographic data recording media made of same DAIKIN INDUSTRIES, LTD. (JP) 2012-06-05 US disclosed
US-20100112460-A1 COMPOSITION FOR FLUORINE-CONTAINING VOLUME HOLOGRAPHIC DATA RECORDING MATERIAL AND FLUORINE-CONTAINING VOLUME HOLOGRAPHIC DATA RECORDING MEDIA MADE OF SAME UMEDA CENTER BUILDING (JP) 2010-05-06 US disclosed