Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | ATM | Q13315 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | ALPG | P10696 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.52 |
| ▸ | BCHE | P06276 | 1/20 | 0.51 |
| ▸ | RELA | Q04206 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21647109 | 0.84 | AR (0.65) | MAPTALDH1A1LMNAATMKMT2A | |
| SCHEMBL29837038 | 0.84 | AR (0.65) | MAPTALDH1A1LMNAATMKMT2A | |
| SCHEMBL21647108 | 0.84 | AR (0.65) | MAPTALDH1A1LMNAATMKMT2A | |
| SCHEMBL3498434 | 0.83 | BCHE (0.63) | MAPTALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL3498432 | 0.83 | BCHE (0.63) | MAPTALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL29843588 | 0.82 | MAPT (0.58) | MAPTALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL7101080 | 0.82 | MAPT (0.58) | MAPTALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL28383313 | 0.82 | MAPT (0.58) | MAPTALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL5093581 | 0.80 | MAPT (0.50) | MAPTALDH1A1LMNAATMKMT2A | |
| Ethyne SCHEMBL27085492 | 0.80 | MAPT (0.55) | MAPTALDH1A1LMNAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110903288-B | Imidazaphenanthridine compound and preparation method and application thereof | 浙江大学 | 2021-02-23 | — | — | CN | disclosed |
| CN-110903288-A | Imidazaphenanthridine compound and preparation method and application thereof | 浙江大学 | 2020-03-24 | — | — | CN | disclosed |