Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | ATM | Q13315 | 3/20 | 0.50 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | ALPG | P10696 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | RELA | Q04206 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5093574 | 0.85 | MAPT (0.49) | MAPTALDH1A1LMNAATMCYP1B1 | |
| SCHEMBL9319237 | 0.83 | MAPT (0.58) | MAPTALDH1A1LMNACYP1B1KMT2A | |
| SCHEMBL6311040 | 0.83 | MAPT (0.58) | MAPTALDH1A1LMNACYP1B1KMT2A | |
| SCHEMBL21647109 | 0.81 | AR (0.65) | MAPTALDH1A1LMNAATMCYP1B1 | |
| SCHEMBL21647108 | 0.81 | AR (0.65) | MAPTALDH1A1LMNAATMCYP1B1 | |
| SCHEMBL29837038 | 0.81 | AR (0.65) | MAPTALDH1A1LMNAATMCYP1B1 | |
| SCHEMBL28387971 | 0.80 | MAPT (0.52) | MAPTALDH1A1LMNAATMCYP1B1 | |
| SCHEMBL9893358 | 0.79 | CYP1B1 (0.69) | MAPTALDH1A1LMNAATMCYP1B1 | |
| SCHEMBL9893359 | 0.79 | CYP1B1 (0.69) | MAPTALDH1A1LMNAATMCYP1B1 | |
| SCHEMBL7583119 | 0.77 | CA1 (0.46) | MAPTLMNAATMCYP1B1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008035086-A2 | SYNTHESIS OF LEUKOTRIENE COMPOUNDS | ALMAC SCIENCES LIMITED (GB) | 2008-03-27 | — | — | WO | disclosed |