Known targets — ChEMBL curated mechanism
FGFR1FGFR2FGFR3FGFR4FLT1FLT4KDRPDGFRAPDGFRB
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR known ✓ | P35968 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.54 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 5/20 | 0.52 |
| ▸ | RAB9A | P51151 | 5/20 | 0.52 |
| ▸ | MEN1 | O00255 | 5/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | GRM4 | Q14833 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.44 |
| ▸ | GRM5 | P41594 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29389283 | 0.82 | MEN1 (0.76) | PTGS1PTGS2NPC1RAB9AMEN1 | |
| SCHEMBL30195162 | 0.82 | MEN1 (0.76) | PTGS1PTGS2NPC1RAB9AMEN1 | |
| SCHEMBL461986 | 0.82 | MEN1 (0.76) | PTGS1PTGS2NPC1RAB9AMEN1 | |
| SCHEMBL461985 | 0.82 | MEN1 (0.76) | PTGS1PTGS2NPC1RAB9AMEN1 | |
| SCHEMBL2572759 | 0.81 | ALDH1A1 (0.52) | PTGS1PTGS2NPC1RAB9AMEN1 | |
| SCHEMBL2572762 | 0.81 | ALDH1A1 (0.52) | PTGS1PTGS2NPC1RAB9AMEN1 | |
| Sulfuric Acid Dimethyl Ester SCHEMBL28003411 | 0.81 | NPC1 (0.52) | PTGS1PTGS2NPC1RAB9AMEN1 | |
| Hydrochloric Acid SCHEMBL8045707 | 0.80 | MEN1 (0.73) | PTGS1PTGS2NPC1RAB9AMEN1 | |
| Hydrochloric Acid SCHEMBL8045709 | 0.80 | MEN1 (0.73) | PTGS1PTGS2NPC1RAB9AMEN1 | |
| Bromide SCHEMBL28164060 | 0.80 | MEN1 (0.73) | PTGS1PTGS2NPC1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111116827-A | High-elasticity high-toughness gel micro-nano particles and preparation method thereof | 西南石油大学 | 2020-05-08 | — | — | CN | claimed |
| CN-111116827-B | High-elasticity high-toughness gel micro-nano particles and preparation method thereof | 西南石油大学 | 2021-11-23 | — | — | CN | disclosed |
| CN-111116827-A | High-elasticity high-toughness gel micro-nano particles and preparation method thereof | 西南石油大学 | 2020-05-08 | — | — | CN | disclosed |