Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.60 |
| ▸ | METAP1 | P53582 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.39 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23474562 | 0.84 | ACHE (0.49) | ACHEMETAP1MAPTKDM4EMEN1 | |
| SCHEMBL17515294 | 0.83 | ACHE (0.55) | ACHEMETAP1MAPTKDM4EMEN1 | |
| SCHEMBL16153700 | 0.80 | MAPT (0.76) | ACHEMETAP1MAPTKDM4EMEN1 | |
| SCHEMBL28390141 | 0.80 | ACHE (0.58) | ACHEMAPTKDM4EMEN1ALDH1A1 | |
| SCHEMBL6881129 | 0.80 | ACHE (0.63) | ACHEMETAP1MAPTKDM4EMEN1 | |
| SCHEMBL9221702 | 0.75 | ACHE (0.50) | ACHEMETAP1MAPTKDM4EALDH1A1 | |
| SCHEMBL2481939 | 0.75 | ACHE (1.00) | ACHEMETAP1HTR2AHTR2CHTR2B | |
| SCHEMBL30702212 | 0.75 | MAPT (0.56) | ACHEMETAP1MAPTKDM4EMEN1 | |
| SCHEMBL3948845 | 0.75 | MAPT (0.56) | ACHEMETAP1MAPTKDM4EMEN1 | |
| SCHEMBL29893908 | 0.75 | ACHE (1.00) | ACHEMETAP1HTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107899611-B | Organic catalyst with visible light catalytic asymmetric photocatalytic hydroxylation performance, preparation method and application thereof | 大连理工大学 | 2020-04-07 | — | — | CN | disclosed |