Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 1/20 | 0.55 |
| ▸ | TTK | P33981 | 3/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28385514 | 0.86 | — | — | |
| SCHEMBL28420032 | 0.85 | ALK (0.54) | ALK | |
| SCHEMBL28887740 | 0.84 | FGFR1 (0.53) | ALK | |
| SCHEMBL28070380 | 0.82 | TTK (0.41) | TTK | |
| SCHEMBL28070379 | 0.79 | — | — | |
| SCHEMBL29847405 | 0.78 | TTK (0.85) | ALKTTK | |
| SCHEMBL16514286 | 0.78 | TTK (0.85) | ALKTTK | |
| SCHEMBL28388126 | 0.76 | — | — | |
| SCHEMBL28387805 | 0.76 | — | — | |
| SCHEMBL28385572 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109851617-B | Chemical entities, compositions, and methods | 润新生物公司 | 2022-08-16 | — | — | CN | disclosed |
| CN-111285813-A | Chemical entities, compositions, and methods | 润新生物公司 | 2020-06-16 | — | — | CN | disclosed |
| CN-105682661-B | Certain chemical entities, compositions, and methods | 润新生物公司 | 2020-03-27 | — | — | CN | disclosed |