Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 3/20 | 0.53 |
| ▸ | KDR | P35968 | 3/20 | 0.53 |
| ▸ | EGFR | P00533 | 14/20 | 0.52 |
| ▸ | FGFR2 | P21802 | 3/20 | 0.49 |
| ▸ | JAK3 | P52333 | 1/20 | 0.48 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28416821 | 0.91 | FGFR1 (0.63) | FGFR1KDREGFRFGFR2JAK3 | |
| SCHEMBL28384151 | 0.91 | ALK (0.47) | EGFRJAK3ALK | |
| SCHEMBL28383470 | 0.90 | JAK3 (0.47) | EGFRJAK3 | |
| SCHEMBL28383183 | 0.89 | EGFR (0.47) | FGFR1KDREGFRJAK3 | |
| SCHEMBL28387179 | 0.89 | EGFR (0.49) | EGFRJAK3ALK | |
| SCHEMBL28385550 | 0.89 | EGFR (0.61) | FGFR1KDREGFRFGFR2 | |
| SCHEMBL28387187 | 0.88 | FGFR1 (0.52) | FGFR1KDREGFRFGFR2 | |
| SCHEMBL28382492 | 0.85 | EGFR (0.51) | FGFR1KDREGFRFGFR2JAK3 | |
| SCHEMBL28887739 | 0.84 | EGFR (0.52) | FGFR1KDREGFRFGFR2JAK3 | |
| SCHEMBL28394159 | 0.84 | ALK (0.55) | ALK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105682661-B | Certain chemical entities, compositions, and methods | 润新生物公司 | 2020-03-27 | — | — | CN | claimed |
| CN-109851617-B | Chemical entities, compositions, and methods | 润新生物公司 | 2022-08-16 | — | — | CN | disclosed |
| CN-111285813-A | Chemical entities, compositions, and methods | 润新生物公司 | 2020-06-16 | — | — | CN | disclosed |
| CN-105682661-B | Certain chemical entities, compositions, and methods | 润新生物公司 | 2020-03-27 | — | — | CN | disclosed |