Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.60 |
| ▸ | CA12 | O43570 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | CA9 | Q16790 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 8/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | MPO | P05164 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28391081 | 0.82 | CA12 (0.61) | KDM4ECA12CA2CA9MAPT | |
| SCHEMBL28390034 | 0.79 | CA12 (0.57) | CA12CA2CA9MAPTSMN1; SMN2 | |
| SCHEMBL28393233 | 0.79 | CA12 (0.57) | CA12CA2CA9MAPTSMN1; SMN2 | |
| SCHEMBL28391082 | 0.79 | CA12 (0.57) | KDM4ECA12CA2CA9MAPT | |
| SCHEMBL28392122 | 0.78 | CA12 (0.75) | KDM4ECA12CA2CA9MAPT | |
| SCHEMBL10867495 | 0.77 | MAPT (0.64) | KDM4ECA12CA2CA9MAPT | |
| SCHEMBL28390935 | 0.76 | GAA (0.71) | KDM4ECA12CA2CA9MAPT | |
| SCHEMBL28389595 | 0.76 | CA12 (0.53) | KDM4ECA12CA2CA9MAPT | |
| SCHEMBL9751987 | 0.73 | HSPA5 (0.57) | KDM4EMEN1KMT2ARAB9AMAOB | |
| SCHEMBL13578588 | 0.71 | KDM4E (0.49) | KDM4EGAALMNAL3MBTL1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111116570-A | Pyrimidine dibenzo [ b, f ] [1,4] oxazepine derivatives and preparation method thereof | 浙江大学 | 2020-05-08 | — | — | CN | disclosed |