Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.71 |
| ▸ | LMNA | P02545 | 2/20 | 0.71 |
| ▸ | MAPT | P10636 | 6/20 | 0.53 |
| ▸ | MEN1 | O00255 | 5/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | CA12 | O43570 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28391081 | 0.81 | CA12 (0.61) | GAALMNAMAPTMEN1KMT2A | |
| SCHEMBL28390034 | 0.78 | CA12 (0.57) | GAALMNAMAPTMEN1KMT2A | |
| SCHEMBL28391082 | 0.78 | CA12 (0.57) | GAALMNAMAPTMEN1KMT2A | |
| SCHEMBL28393233 | 0.78 | CA12 (0.57) | GAALMNAMAPTMEN1KMT2A | |
| SCHEMBL28392122 | 0.77 | CA12 (0.75) | GAALMNAMAPTMEN1KMT2A | |
| SCHEMBL30003353 | 0.76 | LMNA (0.52) | GAALMNAMAPTMEN1KMT2A | |
| SCHEMBL27769271 | 0.76 | MAPT (0.68) | GAAMAPTMEN1KMT2ACA12 | |
| SCHEMBL28394412 | 0.76 | KDM4E (0.60) | GAALMNAMAPTMEN1KMT2A | |
| SCHEMBL15435400 | 0.76 | GAA (0.54) | GAALMNAMAPTMEN1KMT2A | |
| SCHEMBL27912688 | 0.75 | MAPT (0.66) | GAALMNAMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111116570-A | Pyrimidine dibenzo [ b, f ] [1,4] oxazepine derivatives and preparation method thereof | 浙江大学 | 2020-05-08 | — | — | CN | disclosed |