Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.67 |
| ▸ | KDM4A | O75164 | 3/20 | 0.67 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.67 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.67 |
| ▸ | KDM6B | O15054 | 1/20 | 0.67 |
| ▸ | KDM6A | O15550 | 1/20 | 0.67 |
| ▸ | TET3 | O43151 | 1/20 | 0.67 |
| ▸ | KDM4B | O94953 | 1/20 | 0.67 |
| ▸ | KDM5C | P41229 | 1/20 | 0.67 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.67 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.67 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.67 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.67 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.67 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.67 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.67 |
| ▸ | COMT | P21964 | 2/20 | 0.59 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10157045 | 0.84 | KDM4E (0.67) | KDM4EL3MBTL1KDM4AKDM4CEGLN1 | |
| SCHEMBL7956981 | 0.84 | KDM4E (0.66) | KDM4EL3MBTL1KDM4AKDM4CEGLN1 | |
| SCHEMBL7969726 | 0.83 | KDM4E (0.65) | KDM4EL3MBTL1KDM4AKDM4CEGLN1 | |
| SCHEMBL29462403 | 0.82 | KDM4E (0.73) | KDM4EL3MBTL1KDM4AKDM4CEGLN1 | |
| SCHEMBL163474 | 0.82 | KDM4E (0.73) | KDM4EL3MBTL1KDM4AKDM4CEGLN1 | |
| SCHEMBL15170803 | 0.82 | KDM4E (0.63) | KDM4EL3MBTL1KDM4AKDM4CEGLN1 | |
| SCHEMBL27468637 | 0.82 | KDM4E (0.77) | KDM4EL3MBTL1KDM4AKDM4CEGLN1 | |
| Hydrochloric Acid SCHEMBL3310696 | 0.81 | KDM4E (0.71) | KDM4EL3MBTL1KDM4AKDM4CEGLN1 | |
| SCHEMBL2849950 | 0.81 | PDE4A (0.60) | KDM4EKDM4AKDM4CGAAMEN1 | |
| SCHEMBL10721794 | 0.81 | KDM4E (0.73) | KDM4EL3MBTL1KDM4AKDM4CEGLN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108348894-A | Ozonolysis for compound activation and ozonolysis | 空气交叉股份有限公司 | 2018-07-31 | — | — | CN | disclosed |
| US-20100160335-A1 | PYRIDAZINONE DERIVATIVE AND PDE INHIBITOR CONTAINING THE SAME AS ACTIVE INGREDIENT | KYORIN PHARMACEUTICAL CO., LTD. | 2010-06-24 | — | — | US | disclosed |
| US-20100130738-A1 | PYRAZOLONE DERIVATIVE AND PDE INHIBITOR CONTAINING THE SAME AS ACTIVE INGREDIENT | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2010-05-27 | — | — | US | disclosed |
| EP-2168959-A1 | PYRIDAZINONE DERIVATIVE AND PDE INHIBITOR CONTAINING THE SAME AS ACTIVE INGREDIENT | Kyorin Pharmaceutical Co., Ltd. (JP) | 2010-03-31 | — | — | EP | disclosed |
| EP-2168960-A1 | PYRAZOLONE DERIVATIVE AND PDE INHIBITOR CONTAINING THE SAME AS ACTIVE INGREDIENT | Kyorin Pharmaceutical Co., Ltd. (JP) | 2010-03-31 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100130738-A1 | PYRAZOLONE DERIVATIVE AND PDE INHIBITOR CONTAINING THE SAME AS ACTIVE INGREDIENT | PDE3A, PDE3B, PDE2A | KDM4E 1383/4885L3MBTL1 4431/4885KDM4A 768/4885 |
| US-20100160335-A1 | PYRIDAZINONE DERIVATIVE AND PDE INHIBITOR CONTAINING THE SAME AS ACTIVE INGREDIENT | PDE3A, PDE5A, PDE2A | KDM4E 811/4885L3MBTL1 4430/4885KDM4A 508/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.