Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.47 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.47 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.45 |
| ▸ | F10 | P00742 | 1/20 | 0.45 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | MAOB | P27338 | 7/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.41 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29576029 | 0.80 | CA12 (0.43) | CA12CA2CA9MAOBCA1 | |
| SCHEMBL28396007 | 0.78 | MAOB (0.62) | CYP4F2CYP4A11MAOBMAOA | |
| SCHEMBL28398195 | 0.77 | BCHE (0.53) | CYP4F2CYP4A11F10MAOBMAOA | |
| SCHEMBL1889801 | 0.77 | MAOB (0.67) | MAOBMAOAMRGPRX4 | |
| SCHEMBL28398922 | 0.76 | MAOB (0.66) | MAOBMAOAMRGPRX4 | |
| SCHEMBL20590908 | 0.76 | CYP4F2 (0.58) | CYP4F2CYP4A11NR1H3F10NR1H2 | |
| SCHEMBL13338101 | 0.74 | MAOB (0.59) | CA12CA2CA9MAOBCA1 | |
| SCHEMBL28399599 | 0.73 | MAOB (0.57) | MAOBMAOAMRGPRX4 | |
| SCHEMBL1887354 | 0.72 | MAOB (0.62) | CA12CA2CA9MAOBCA1 | |
| SCHEMBL31163946 | 0.72 | MAOB (0.47) | CYP4F2CYP4A11MAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107344940-B | BTK inhibitors and uses thereof | 广东东阳光药业有限公司 | 2020-04-21 | — | — | CN | disclosed |