SCHEMBL31163946

SCHEMBL31163946

C#CCOc1cccc(COc2cc(CBr)cc(CBr)c2)c1

nearest known ligand 0.47

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ MAOB P27338 14/20 0.47
▸ F2 P00734 2/20 0.42
▸ BCHE P06276 3/20 0.41
▸ CYP4F2 P78329 1/20 0.41
▸ CYP4A11 Q02928 1/20 0.41
▸ MAOA P21397 3/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11200381 0.88 MAOB (0.49) MAOBBCHEMAOA
SCHEMBL25204850 0.88 GSTP1 (0.38) MAOBBCHEMAOA
SCHEMBL28398195 0.84 BCHE (0.53) MAOBBCHECYP4F2CYP4A11MAOA
SCHEMBL13591059 0.84 GSTP1 (0.38) MAOBBCHEMAOA
SCHEMBL13591054 0.84 GSTP1 (0.38) MAOBBCHEMAOA
SCHEMBL13591061 0.84 GSTP1 (0.38) MAOBBCHEMAOA
SCHEMBL28399599 0.81 MAOB (0.57) MAOBMAOA
SCHEMBL13591057 0.81 GSTP1 (0.42) MAOBMAOA
SCHEMBL28396007 0.80 MAOB (0.62) MAOBBCHECYP4F2CYP4A11MAOA
SCHEMBL31163949 0.79 GSTP1 (0.39) MAOBMAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240342301-A1 ANTIBODY-DRUG CONJUGATES MC SAF (FR) 2024-10-17 — — US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240342301-A1 ANTIBODY-DRUG CONJUGATES FCGRT, FCGR3B, FCGR2A MAOB 1148/4885F2 2185/4885BCHE 110/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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