SCHEMBL28396304

SCHEMBL28396304

CC12CC3CC(C)(C1)CC(NC(=O)Nc1ccccn1)(C3)C2

nearest known ligand 0.69

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 15/20 0.69
TSHR P16473 1/20 0.69
MAPK1 P28482 1/20 0.69
RAB9A P51151 1/20 0.69

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28888905 0.81 EPHX2 (0.76) EPHX2
SCHEMBL28392233 0.79 EPHX2 (0.55) EPHX2TSHRMAPK1RAB9A
SCHEMBL28396308 0.78 EPHX2 (0.76) EPHX2
SCHEMBL28401568 0.77 EPHX2 (0.70) EPHX2RAB9A
SCHEMBL28393940 0.76 EPHX2 (0.62) EPHX2
SCHEMBL28395025 0.76 EPHX2 (0.62) EPHX2
SCHEMBL16073075 0.76 EPHX2 (0.69) EPHX2TSHRRAB9A
SCHEMBL28393937 0.74 EPHX2 (0.66) EPHX2
SCHEMBL28393267 0.74 EPHX2 (0.76) EPHX2
SCHEMBL28395860 0.74 EPHX2 (0.76) EPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107417578-B N- (3, 5-dimethyl adamantane-1-yl) -N' -substituted phenylurea compound and preparation method and application thereof 沈阳海诺威医药科技有限公司 2020-02-07 CN claimed
CN-107417578-B N- (3, 5-dimethyl adamantane-1-yl) -N' -substituted phenylurea compound and preparation method and application thereof 沈阳海诺威医药科技有限公司 2020-02-07 CN disclosed