Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 17/20 | 0.76 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.55 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.55 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.55 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.55 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.55 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.55 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.55 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28393940 | 0.86 | EPHX2 (0.62) | EPHX2 | |
| SCHEMBL6720873 | 0.85 | EPHX2 (0.55) | EPHX2GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL28888905 | 0.83 | EPHX2 (0.76) | EPHX2 | |
| SCHEMBL28393937 | 0.79 | EPHX2 (0.66) | EPHX2 | |
| SCHEMBL9316491 | 0.79 | SIGMAR1 (0.51) | EPHX2GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL28395055 | 0.79 | EPHX2 (0.59) | EPHX2 | |
| SCHEMBL28395025 | 0.78 | EPHX2 (0.62) | EPHX2 | |
| SCHEMBL28395028 | 0.78 | EPHX2 (0.71) | EPHX2 | |
| SCHEMBL28396304 | 0.78 | EPHX2 (0.69) | EPHX2 | |
| SCHEMBL28393267 | 0.76 | EPHX2 (0.76) | EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107417578-B | N- (3, 5-dimethyl adamantane-1-yl) -N' -substituted phenylurea compound and preparation method and application thereof | 沈阳海诺威医药科技有限公司 | 2020-02-07 | — | — | CN | claimed |
| CN-107417578-B | N- (3, 5-dimethyl adamantane-1-yl) -N' -substituted phenylurea compound and preparation method and application thereof | 沈阳海诺威医药科技有限公司 | 2020-02-07 | — | — | CN | disclosed |