SCHEMBL28396409

SCHEMBL28396409

COc1cc2c(cc1OC)C(=O)C(C(=O)OC(C)(C)C)C2

nearest known ligand 0.61

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5358840 0.87 ACHE (0.59) ACHE
SCHEMBL4859012 0.82 ACHE (0.61) ACHE
SCHEMBL4726216 0.82 KDM4E (0.78)
SCHEMBL3085511 0.81 ACHE (0.59) ACHE
SCHEMBL3085512 0.81 ACHE (0.59) ACHE
SCHEMBL15899217 0.78 KDM4E (0.56)
SCHEMBL28391460 0.77 ACHE (0.48) ACHE
SCHEMBL22394534 0.76
SCHEMBL28909964 0.76 KDM4E (0.47)
SCHEMBL29769613 0.75 MAPT (0.49) ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107899611-B Organic catalyst with visible light catalytic asymmetric photocatalytic hydroxylation performance, preparation method and application thereof 大连理工大学 2020-04-07 CN disclosed