Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 9/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | DDX3X | O00571 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21749240 | 0.85 | ABCG2 (0.43) | ABCG2ABCB1SMN1; SMN2MAPTDDX3X | |
| SCHEMBL20552459 | 0.85 | ABCG2 (0.47) | ABCG2ABCB1SMN1; SMN2MAPTDDX3X | |
| SCHEMBL20552901 | 0.83 | ABCG2 (0.41) | ABCG2ABCB1SMN1; SMN2MAPTDDX3X | |
| SCHEMBL25787836 | 0.83 | ABCG2 (0.41) | ABCG2ABCB1SMN1; SMN2MAPTDDX3X | |
| SCHEMBL20551929 | 0.83 | USP2 (0.48) | ABCG2ABCB1SMN1; SMN2MAPTDDX3X | |
| SCHEMBL20553472 | 0.82 | ABCG2 (0.46) | ABCG2ABCB1SMN1; SMN2MAPTDDX3X | |
| SCHEMBL21749269 | 0.82 | ABCG2 (0.46) | ABCG2ABCB1SMN1; SMN2MAPTDDX3X | |
| SCHEMBL20552265 | 0.81 | ABCG2 (0.45) | ABCG2ABCB1SMN1; SMN2MAPTDDX3X | |
| SCHEMBL20552643 | 0.81 | ABCG2 (0.47) | ABCG2ABCB1SMN1; SMN2MAPTDDX3X | |
| SCHEMBL20552624 | 0.81 | ABCG2 (0.47) | ABCG2ABCB1SMN1; SMN2MAPTDDX3X |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111132673-A | Non-fused tricyclic compounds | 维瓦斯治疗公司 | 2020-05-08 | — | — | CN | disclosed |