SCHEMBL28397207

SCHEMBL28397207

CC(=O)OC(=O)CN(C(C)=O)C(=O)CN

nearest known ligand 0.33

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.33
TSHR P16473 1/20 0.33
MGAM O43451 1/20 0.32
GAA P10253 1/20 0.32
SI P14410 1/20 0.32
MGAM2 Q2M2H8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27293706 0.92 ALDH1A1 (0.36) ALDH1A1TSHRMGAMGAASI
SCHEMBL28027529 0.84 MGAM (0.34) MGAMGAASIMGAM2
SCHEMBL21955799 0.75 GLRA1 (0.39) TSHR
SCHEMBL9394064 0.74 CHRM2 (0.38) ALDH1A1TSHRMGAMGAASI
SCHEMBL27804594 0.72 HDAC6 (0.37)
SCHEMBL22371 0.71
SCHEMBL21955843 0.71
SCHEMBL28079053 0.71 TSHR (0.33) TSHR
Water SCHEMBL29832019 0.69
SCHEMBL1321713 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111072507-A DL-neopentyl glycine intermediate, preparation method thereof and preparation method of derivative based on intermediate 南京德尔诺医药科技有限公司 2020-04-28 CN disclosed