Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.69 |
| ▸ | SGMS2 | Q8NHU3 | 3/20 | 0.68 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | KDM5A | P29375 | 1/20 | 0.53 |
| ▸ | SLC6A12 | P48065 | 1/20 | 0.51 |
| ▸ | CNR2 | P34972 | 3/20 | 0.50 |
| ▸ | CNR1 | P21554 | 2/20 | 0.50 |
| ▸ | HTR7 | P34969 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28402448 | 0.91 | MEN1 (0.70) | MEN1KMT2AALDH1A1SGMS2TSHR | |
| SCHEMBL28890111 | 0.88 | MEN1 (0.69) | MEN1KMT2AALDH1A1SGMS2TSHR | |
| SCHEMBL28402827 | 0.86 | MEN1 (0.64) | MEN1KMT2AALDH1A1SGMS2 | |
| SCHEMBL28398682 | 0.85 | MEN1 (0.62) | MEN1KMT2AALDH1A1SGMS2TSHR | |
| SCHEMBL28397279 | 0.85 | POLB (0.66) | MEN1KMT2AALDH1A1SGMS2TSHR | |
| SCHEMBL28397282 | 0.84 | MEN1 (0.61) | MEN1KMT2AALDH1A1SGMS2TSHR | |
| SCHEMBL28406339 | 0.84 | KMT2A (0.67) | MEN1KMT2AALDH1A1SGMS2TSHR | |
| SCHEMBL28235069 | 0.84 | ALDH1A1 (0.57) | MEN1KMT2AALDH1A1SGMS2TSHR | |
| SCHEMBL28402751 | 0.83 | KMT2A (0.62) | MEN1KMT2AALDH1A1SGMS2 | |
| SCHEMBL28406276 | 0.81 | KMT2A (0.67) | MEN1KMT2AALDH1A1SGMS2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108440389-B | 3,4, 5-trihydroxybenzoic acid derivative and preparation method and application thereof | 山东大学 | 2020-05-29 | — | — | CN | disclosed |