SCHEMBL28397392

SCHEMBL28397392

C=CCCCCCC[Si](Cl)(CCCCCCC=C)C(C)C

nearest known ligand 0.43

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.43
ALDH1A1 P00352 2/20 0.36
LMNA P02545 3/20 0.33
MAPT P10636 2/20 0.33
ABCC4 O15439 1/20 0.33
TRPA1 O75762 1/20 0.31
USP2 O75604 1/20 0.30
CYP3A4 P08684 1/20 0.30
RECQL P46063 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL38660389 1.00 TSHR (0.43) TSHRALDH1A1LMNAMAPTABCC4
SCHEMBL38658266 1.00 TSHR (0.43) TSHRALDH1A1LMNAMAPTABCC4
SCHEMBL28401802 1.00 TSHR (0.43) TSHRALDH1A1LMNAMAPTABCC4
SCHEMBL28398212 0.98 TSHR (0.39) TSHRALDH1A1LMNAMAPTABCC4
SCHEMBL28404239 0.91 TSHR (0.39) TSHRALDH1A1
SCHEMBL31414054 0.83 TSHR (0.43) TSHRALDH1A1LMNAMAPTABCC4
SCHEMBL28890074 0.82 TSHR (0.33) TSHRALDH1A1
SCHEMBL31414065 0.81 TSHR (0.39) TSHRALDH1A1LMNAMAPTABCC4
SCHEMBL6063976 0.76 TSHR (0.48) TSHRALDH1A1LMNAMAPTABCC4
SCHEMBL389625 0.76 TSHR (0.48) TSHRALDH1A1LMNAMAPTABCC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111138569-A Organosilane compound, polyolefin resin, and preparation method and application thereof 中国科学院化学研究所 2020-05-12 CN claimed
CN-122036997-A Modified polyolefin catalyst and preparation method and application thereof 中国石油天然气股份有限公司 2026-05-15 CN disclosed
CN-111138569-A Organosilane compound, polyolefin resin, and preparation method and application thereof 中国科学院化学研究所 2020-05-12 CN disclosed