Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAT | P00750 | 9/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.35 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.35 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.34 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.34 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.34 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20914416 | 0.81 | BRD4 (0.39) | PLATPTGS2PDGFRAMAPK8CDK5 | |
| SCHEMBL20914302 | 0.79 | CDK5 (0.35) | PDGFRAMAPK8CDK5CLK4 | |
| SCHEMBL20913985 | 0.76 | PLAT (0.39) | PLATPTGS2PDGFRAMAPK8CDK5 | |
| SCHEMBL16792069 | 0.68 | ALKBH3 (0.43) | PLAT | |
| SCHEMBL20913970 | 0.68 | HSD17B10 (0.47) | PLAT | |
| SCHEMBL12746789 | 0.67 | ALOX15 (0.55) | CREBBP | |
| SCHEMBL17147910 | 0.66 | CREBBP (0.39) | PLATCREBBP | |
| SCHEMBL16092479 | 0.65 | MDM2 (0.52) | PLATPDGFRAMAPK8CDK5CLK4 | |
| SCHEMBL16535047 | 0.65 | AURKA (0.46) | PLAT | |
| SCHEMBL16535142 | 0.64 | GRM4 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111212839-A | Pyrazolopyrimidinone compounds and uses thereof | 艾杜罗生物科技公司 | 2020-05-29 | — | — | CN | disclosed |