Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17645404 | 0.91 | TGFBR1 (0.64) | TGFBR1TGFB1 | |
| SCHEMBL22186847 | 0.89 | TGFBR1 (0.60) | TGFBR1TGFB1 | |
| SCHEMBL28888969 | 0.85 | TGFBR1 (0.57) | TGFBR1TGFB1 | |
| SCHEMBL29100047 | 0.85 | TGFBR1 (0.49) | TGFBR1TGFB1 | |
| SCHEMBL17645167 | 0.85 | TGFBR1 (0.57) | TGFBR1TGFB1 | |
| SCHEMBL17645445 | 0.83 | TGFBR1 (0.53) | TGFBR1TGFB1 | |
| SCHEMBL24263214 | 0.81 | TGFBR1 (0.52) | TGFBR1TGFB1 | |
| SCHEMBL17645399 | 0.81 | TGFBR1 (0.52) | TGFBR1TGFB1 | |
| SCHEMBL22186882 | 0.80 | TGFBR1 (0.51) | TGFBR1TGFB1 | |
| SCHEMBL17645364 | 0.78 | TGFBR1 (0.47) | TGFBR1TGFB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111196804-B | TGF-beta R1 inhibitors and uses thereof | 南京圣和药业股份有限公司 | 2023-11-07 | — | — | CN | disclosed |
| CN-111196804-A | TGF- β R1 inhibitor and application thereof | 南京圣和药业股份有限公司 | 2020-05-26 | — | — | CN | disclosed |