Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 6/20 | 0.44 |
| ▸ | CA1 | P00915 | 4/20 | 0.42 |
| ▸ | CA2 | P00918 | 4/20 | 0.42 |
| ▸ | CA12 | O43570 | 3/20 | 0.42 |
| ▸ | CA7 | P43166 | 3/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.39 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.39 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9101971 | 0.86 | PTGDR2 (0.39) | EPHX2CA1CA2KMT2AMAPT | |
| SCHEMBL28851424 | 0.84 | JAK2 (0.44) | EPHX2KMT2AMAPTL3MBTL1 | |
| SCHEMBL29062245 | 0.84 | JAK2 (0.44) | EPHX2KMT2AMAPTL3MBTL1 | |
| SCHEMBL6942857 | 0.84 | JAK2 (0.44) | EPHX2KMT2AMAPTL3MBTL1 | |
| SCHEMBL2217850 | 0.82 | PTGDR2 (0.46) | EPHX2KMT2AMAPTMEN1 | |
| SCHEMBL3387056 | 0.80 | PTGDR2 (0.36) | EPHX2CA1CA2KMT2AMAPT | |
| SCHEMBL5278348 | 0.80 | PTGDR2 (0.47) | EPHX2KMT2AMAPTMEN1 | |
| SCHEMBL30764027 | 0.80 | PTGDR2 (0.43) | EPHX2L3MBTL1 | |
| SCHEMBL778056 | 0.79 | PTGDR2 (0.35) | EPHX2CA1CA2KMT2AMAPT | |
| SCHEMBL361128 | 0.79 | PTGDR2 (0.49) | EPHX2KMT2AMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111032641-A | Substituted 5-cyanoindole compounds and uses thereof | 诺华股份有限公司 | 2020-04-17 | — | — | CN | disclosed |