SCHEMBL28397888

SCHEMBL28397888

CC(C)(C)c1ccc(C(=O)c2ccccc2)c(C(=O)c2ccccc2)c1C(C)(C)C

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ELANE P08246 2/20 0.43
AKR1C3 P42330 1/20 0.43
ALDH1A1 P00352 3/20 0.42
KDM4E B2RXH2 2/20 0.41
GAA P10253 2/20 0.41
MEN1 O00255 2/20 0.41
USP2 O75604 2/20 0.41
KMT2A Q03164 2/20 0.41
KEAP1 Q14145 1/20 0.41
NFE2L2 Q16236 1/20 0.41
MAPT P10636 3/20 0.41
MAPK1 P28482 3/20 0.41
HSD17B10 Q99714 2/20 0.41
ALOX15 P16050 1/20 0.41
LMNA P02545 2/20 0.40
GLA P06280 1/20 0.40
MYC P01106 1/20 0.40
TDP1 Q9NUW8 2/20 0.40
CYP1A2 P05177 1/20 0.40
PGR P06401 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28688010 0.85 MAPT (0.50) ELANEAKR1C3ALDH1A1KDM4EGAA
SCHEMBL28136021 0.84 MAPT (0.46) ELANEAKR1C3ALDH1A1KDM4EGAA
SCHEMBL2033555 0.83 AKR1C3 (0.52) ELANEAKR1C3ALDH1A1KDM4EGAA
SCHEMBL27489647 0.81 AKR1C3 (0.48) ELANEAKR1C3ALDH1A1GAAMEN1
Ammonia Solution, Strong SCHEMBL27850362 0.80 AKR1C3 (0.47) ELANEAKR1C3ALDH1A1GAAMEN1
SCHEMBL28762390 0.80 TNFRSF1A (0.47) ELANEAKR1C3ALDH1A1KDM4EGAA
SCHEMBL28787250 0.78 AKR1C3 (0.44) ELANEAKR1C3ALDH1A1KDM4EGAA
SCHEMBL2319763 0.77 AKR1C3 (0.55) ELANEAKR1C3ALDH1A1GAAMEN1
SCHEMBL31031098 0.77 AKR1C3 (0.55) ELANEAKR1C3ALDH1A1GAAMEN1
SCHEMBL12251298 0.77 TP53 (0.49) ELANEAKR1C3GAAMAPTMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111218021-A Vitrified dilatant polymer foam hybrid material 翁秋梅 2020-06-02 CN disclosed
CN-111166031-A Dilatancy nature electronic product protective sheath/shell 翁秋梅 2020-05-19 CN disclosed
CN-111171329-A Plastic dilatancy polymer and method for realizing dilatancy thereof 翁秋梅 2020-05-19 CN disclosed
CN-111171364-A Force-responsive polymer foam particle and preparation method thereof 翁秋梅 2020-05-19 CN disclosed
CN-111171330-A Force-responsive dilatancy polymer and method for realizing dilatancy 翁秋梅 2020-05-19 CN disclosed
CN-111171365-A Force-responsive polymer foam composite material 翁秋梅 2020-05-19 CN disclosed