Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAP | Q12884 | 2/20 | 0.69 |
| ▸ | CYP3A4 | P08684 | 14/20 | 0.52 |
| ▸ | SERPINA3 | P01011 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 14/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28398140 | 1.00 | FAP (0.69) | FAPCYP3A4SERPINA3CYP2D6 | |
| SCHEMBL28398142 | 1.00 | FAP (0.69) | FAPCYP3A4SERPINA3CYP2D6 | |
| Fumaric Acid SCHEMBL28393666 | 0.97 | FAP (0.72) | FAPCYP3A4SERPINA3CYP2D6 | |
| Fumaric Acid SCHEMBL28393664 | 0.97 | FAP (0.72) | FAPCYP3A4SERPINA3CYP2D6 | |
| SCHEMBL20041164 | 0.87 | CYP3A4 (0.55) | FAPCYP3A4SERPINA3CYP2D6 | |
| SCHEMBL24808634 | 0.84 | CYP3A4 (0.55) | FAPCYP3A4SERPINA3CYP2D6 | |
| SCHEMBL24808637 | 0.84 | CYP3A4 (0.55) | FAPCYP3A4SERPINA3CYP2D6 | |
| SCHEMBL24808639 | 0.84 | CYP3A4 (0.55) | FAPCYP3A4SERPINA3CYP2D6 | |
| SCHEMBL20041172 | 0.83 | FAP (0.60) | FAPCYP3A4CYP2D6 | |
| SCHEMBL20041219 | 0.83 | FAP (0.60) | FAPCYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111018915-A | Tenofovir styrene acrylate based phosphoramidate compound and pharmaceutical composition and application thereof | 佛山科学技术学院 | 2020-04-17 | — | — | CN | disclosed |