Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | GRM4 | Q14833 | 3/20 | 0.48 |
| ▸ | CLK1 | P49759 | 1/20 | 0.42 |
| ▸ | CLK2 | P49760 | 1/20 | 0.42 |
| ▸ | CTSA | P10619 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ECE1 | P42892 | 1/20 | 0.40 |
| ▸ | GNE | Q9Y223 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29723811 | 0.87 | KDM4E (0.70) | KDM4EALOX15TSHRACMSDTDP1 | |
| SCHEMBL107964 | 0.87 | KDM4E (0.70) | KDM4EALOX15TSHRACMSDTDP1 | |
| Hydrochloric Acid SCHEMBL11682457 | 0.85 | KDM4E (0.67) | KDM4EALOX15TSHRACMSDTDP1 | |
| SCHEMBL29995439 | 0.80 | MAPT (0.58) | KDM4ETSHRGRM4CLK1CLK2 | |
| SCHEMBL4315950 | 0.80 | MAPT (0.58) | KDM4ETSHRGRM4CLK1CLK2 | |
| SCHEMBL2632248 | 0.77 | ALDH1A1 (0.47) | KDM4EALOX15TSHRACMSDTDP1 | |
| SCHEMBL29509427 | 0.74 | KDM4E (0.68) | KDM4EALOX15TSHRACMSDTDP1 | |
| SCHEMBL1500410 | 0.74 | KDM4E (0.68) | KDM4EALOX15TSHRACMSDTDP1 | |
| SCHEMBL3552924 | 0.73 | KDM4E (0.46) | KDM4EALOX15TSHRACMSDTDP1 | |
| Hydrochloric Acid SCHEMBL9426978 | 0.73 | KDM4E (0.65) | KDM4EALOX15TSHRACMSDTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111201228-A | 6-amino-7, 9-dihydro-8H-purin-8-one derivatives as Toll-like receptor 7(TLR7) agonists | 百时美施贵宝公司 | 2020-05-26 | — | — | CN | disclosed |