Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 18/20 | 0.56 |
| ▸ | TDO2 | P48775 | 17/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20743922 | 0.85 | IDO1 (0.47) | IDO1TDO2GAA | |
| SCHEMBL22188385 | 0.83 | IDO1 (0.46) | IDO1TDO2GAA | |
| SCHEMBL20743379 | 0.80 | IDO1 (0.52) | IDO1TDO2 | |
| SCHEMBL28401002 | 0.80 | IDO1 (0.56) | IDO1TDO2 | |
| SCHEMBL28396343 | 0.77 | IDO1 (0.52) | IDO1TDO2 | |
| SCHEMBL20743949 | 0.72 | IDO1 (1.00) | IDO1TDO2 | |
| SCHEMBL28397264 | 0.71 | IDO1 (0.50) | IDO1TDO2 | |
| SCHEMBL20743924 | 0.71 | IDO1 (0.47) | IDO1TDO2 | |
| SCHEMBL28399085 | 0.71 | IDO1 (0.52) | IDO1TDO2 | |
| SCHEMBL28394123 | 0.68 | IDO1 (0.51) | IDO1TDO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110997682-A | Inhibitors of indoleamine 2, 3-dioxygenase and/or tryptophan 2, 3-dioxygenase | 爱杜西亚药品有限公司 | 2020-04-10 | — | — | CN | disclosed |