Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | NOX4 | Q9NPH5 | 3/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.34 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.34 |
| ▸ | GPR6 | P46095 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | DHFR | P00374 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28400195 | 0.86 | SMN1; SMN2 (0.39) | SMN1; SMN2CHRNA1CHRNA3CHRNA7HSD11B1 | |
| SCHEMBL28888725 | 0.86 | POLB (0.43) | FBP1SMN1; SMN2CHRNA1CHRNA3CHRNA7 | |
| SCHEMBL28398857 | 0.83 | SMN1; SMN2 (0.37) | SMN1; SMN2CHRNA1CHRNA3CHRNA7HSD11B1 | |
| SCHEMBL9207922 | 0.82 | SMN1; SMN2 (0.47) | FBP1SMN1; SMN2CHRNA1CHRNA3CHRNA7 | |
| SCHEMBL28402262 | 0.82 | SMN1; SMN2 (0.41) | FBP1SMN1; SMN2CHRNA1CHRNA3CHRNA7 | |
| SCHEMBL28400518 | 0.82 | SMN1; SMN2 (0.41) | FBP1SMN1; SMN2CHRNA1CHRNA3CHRNA7 | |
| SCHEMBL28401068 | 0.80 | SMN1; SMN2 (0.40) | SMN1; SMN2CHRNA1CHRNA3CHRNA7PTGS1 | |
| SCHEMBL28132723 | 0.79 | SMN1; SMN2 (0.63) | FBP1SMN1; SMN2MAOBCHRNA1CHRNA3 | |
| SCHEMBL28396602 | 0.78 | SMN1; SMN2 (0.42) | SMN1; SMN2CHRNA1CHRNA3CHRNA7MEN1 | |
| SCHEMBL28400163 | 0.78 | MAPT (0.47) | FBP1SMN1; SMN2CA2MEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111165505-A | Use of eight-membered oxygen bridged heterocyclic compounds as bee selective insecticide synergists | 华东理工大学 | 2020-05-19 | — | — | CN | disclosed |