Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.42 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.42 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.37 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.37 |
| ▸ | HTR3B | O95264 | 1/20 | 0.37 |
| ▸ | HTR3A | P46098 | 1/20 | 0.37 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.37 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | FBP1 | P09467 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | GPX4 | P36969 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28888725 | 0.87 | POLB (0.43) | SMN1; SMN2CHRNA1CHRNA3CHRNA7ADRB1 | |
| SCHEMBL6852000 | 0.82 | SMN1; SMN2 (0.63) | SMN1; SMN2CHRNA1CHRNA3CHRNA7 | |
| SCHEMBL6852003 | 0.82 | SMN1; SMN2 (0.63) | SMN1; SMN2CHRNA1CHRNA3CHRNA7 | |
| SCHEMBL9408589 | 0.78 | SMN1; SMN2 (0.73) | SMN1; SMN2CHRNA1CHRNA3CHRNA7MAPT | |
| SCHEMBL9408584 | 0.78 | SMN1; SMN2 (0.73) | SMN1; SMN2CHRNA1CHRNA3CHRNA7MAPT | |
| SCHEMBL9217916 | 0.77 | SMN1; SMN2 (0.46) | SMN1; SMN2CHRNA1CHRNA3CHRNA7MAPT | |
| SCHEMBL9217910 | 0.77 | SMN1; SMN2 (0.46) | SMN1; SMN2CHRNA1CHRNA3CHRNA7MAPT | |
| SCHEMBL9217044 | 0.75 | CHRNA3 (0.64) | SMN1; SMN2CHRNA1CHRNA3CHRNA7MAPT | |
| SCHEMBL9217051 | 0.75 | CHRNA3 (0.64) | SMN1; SMN2CHRNA1CHRNA3CHRNA7MAPT | |
| SCHEMBL1250720 | 0.74 | SMN1; SMN2 (0.46) | SMN1; SMN2CHRNA1CHRNA3CHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105557709-A | Application of eight-membered oxygen-bridge heterocyclic compound as pesticide synergist | UNIV NANJING AGRICULTURAL | 2016-05-11 | — | — | CN | disclosed |
| EP-0369526-B1 | Nitromethylene compounds, their preparation and their use as pesticides | SHELL INT RESEARCH (NL) | 1995-07-26 | — | — | EP | disclosed |
| US-5039686-A | Insecticides | SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) | 1991-08-13 | — | — | US | disclosed |
| EP-0369526-A2 | Nitromethylene compounds, their preparation and their use as pesticides | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1990-05-23 | — | — | EP | disclosed |