SCHEMBL28400613

SCHEMBL28400613

Cc1[nH]c(-c2ccncc2)nc1-c1cccc(Cl)c1Cl

nearest known ligand 0.54

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MAPK14 Q16539 12/20 0.54
MAPK13 O15264 8/20 0.54
MAPK12 P53778 8/20 0.54
MAPK11 Q15759 8/20 0.54
RAF1 P04049 6/20 0.54
NPY5R Q15761 3/20 0.46
CDC7 O00311 1/20 0.46
DBF4 Q9UBU7 1/20 0.46
IDO1 P14902 1/20 0.45
GCGR P47871 2/20 0.43
MGAM O43451 1/20 0.43
GAA P10253 1/20 0.43
SI P14410 1/20 0.43
MGAM2 Q2M2H8 1/20 0.43
CSNK1D P48730 2/20 0.43
CSNK1E P49674 2/20 0.43
RHEB Q15382 1/20 0.43
MAPK9 P45984 1/20 0.42
ALOX5 P09917 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31305526 0.89 NPY5R (0.51) MAPK14MAPK13MAPK12MAPK11RAF1
SCHEMBL3137367 0.89 NPY5R (0.51) MAPK14MAPK13MAPK12MAPK11RAF1
SCHEMBL28889078 0.85 NPY5R (0.65) MAPK14MAPK13MAPK12MAPK11RAF1
SCHEMBL28399043 0.84 MAPK13 (0.51) MAPK14MAPK13MAPK12MAPK11RAF1
SCHEMBL31305547 0.83 ENPP1 (0.40) MAPK14MAPK13MAPK12MAPK11RAF1
SCHEMBL14060349 0.83 ENPP1 (0.40) MAPK14MAPK13MAPK12MAPK11RAF1
SCHEMBL28406419 0.81 MAPK13 (0.70) MAPK14MAPK13MAPK12MAPK11RAF1
SCHEMBL28406358 0.81 IDO1 (0.47) MAPK14MAPK13MAPK12MAPK11RAF1
SCHEMBL31305412 0.78 GAA (0.46) MAPK14MGAMGAASIMGAM2
SCHEMBL14060566 0.78 GAA (0.46) MAPK14MGAMGAASIMGAM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111057043-A Imidazole compound, preparation method and application thereof, organic weldable protective agent containing imidazole compound and surface treatment method 深圳市贝加电子材料有限公司 2020-04-24 CN claimed