Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 6/20 | 0.47 |
| ▸ | FGFR1 | P11362 | 6/20 | 0.47 |
| ▸ | KDR | P35968 | 6/20 | 0.47 |
| ▸ | FLT1 | P17948 | 3/20 | 0.47 |
| ▸ | CHEK1 | O14757 | 5/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28393488 | 0.88 | PDGFRB (0.43) | PDGFRBFGFR1KDRCHEK1 | |
| SCHEMBL28403056 | 0.80 | FGFR3 (0.47) | PDGFRBFGFR1KDRFLT1CHEK1 | |
| SCHEMBL28399532 | 0.79 | PDGFRB (0.42) | PDGFRBFGFR1KDRFLT1CHEK1 | |
| SCHEMBL29050756 | 0.79 | PDGFRB (0.41) | PDGFRBFGFR1KDRFLT1CHEK1 | |
| SCHEMBL29050739 | 0.78 | FGFR3 (0.43) | PDGFRBFGFR1KDRCHEK1 | |
| SCHEMBL29050780 | 0.78 | FGFR3 (0.42) | PDGFRBFGFR1KDRFLT1CHEK1 | |
| SCHEMBL29050771 | 0.78 | PDGFRB (0.41) | PDGFRBFGFR1KDRFLT1CHEK1 | |
| SCHEMBL29050751 | 0.77 | FGFR3 (0.41) | PDGFRBFGFR1KDRFLT1CHEK1 | |
| SCHEMBL20599561 | 0.77 | PDGFRB (0.55) | PDGFRBFGFR1KDRFLT1CHEK1 | |
| SCHEMBL30425807 | 0.77 | PDGFRB (0.55) | PDGFRBFGFR1KDRFLT1CHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111032643-A | Quinolinone compounds | 詹森药业有限公司 | 2020-04-17 | — | — | CN | disclosed |