SCHEMBL28401152

SCHEMBL28401152

[c]1ccc2c3cc4ccccc4cc3n(-c3ccccc3)c2c1

nearest known ligand 0.43

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.43
KDM4E B2RXH2 1/20 0.43
ATM Q13315 1/20 0.43
ALDH1A1 P00352 1/20 0.34
TSHR P16473 1/20 0.34
MAT2A P31153 3/20 0.31
MEN1 O00255 1/20 0.31
LMNA P02545 1/20 0.31
KMT2A Q03164 1/20 0.31
GAA P10253 1/20 0.31
GSK3A P49840 1/20 0.31
GSK3B P49841 1/20 0.31
JAK2 O60674 1/20 0.30
JAK3 P52333 1/20 0.30
MAPK8 P45983 1/20 0.30
MAPK9 P45984 1/20 0.30
MAPK1 P28482 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28384188 0.88 L3MBTL1 (0.43) L3MBTL1KDM4EATMALDH1A1TSHR
SCHEMBL974676 0.87 L3MBTL1 (0.56) L3MBTL1KDM4EATMMEN1LMNA
SCHEMBL23079608 0.83 L3MBTL1 (0.54) L3MBTL1KDM4EATMALDH1A1TSHR
SCHEMBL1052701 0.82 L3MBTL1 (0.67) L3MBTL1KDM4EATMALDH1A1MEN1
SCHEMBL16807745 0.81 L3MBTL1 (0.52) L3MBTL1KDM4EATMALDH1A1TSHR
SCHEMBL29031562 0.80 L3MBTL1 (0.46) L3MBTL1KDM4EATMALDH1A1TSHR
SCHEMBL28337233 0.80 L3MBTL1 (0.55) L3MBTL1KDM4EATMALDH1A1TSHR
SCHEMBL30396788 0.80 L3MBTL1 (0.69) L3MBTL1KDM4EATMALDH1A1TSHR
SCHEMBL12774500 0.80 L3MBTL1 (0.69) L3MBTL1KDM4EATMALDH1A1TSHR
SCHEMBL17245477 0.78 L3MBTL1 (0.67) L3MBTL1KDM4EATMALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113429399-B Pyrene derivative, light-emitting device material and light-emitting device 浙江华显光电科技有限公司 2024-03-26 CN disclosed
CN-111116602-B OLED material and application thereof in organic electroluminescent device 北京燕化集联光电技术有限公司 2021-05-14 CN disclosed
CN-111116602-A Novel OLED material and application thereof in organic electroluminescent device 北京燕化集联光电技术有限公司 2020-05-08 CN disclosed