Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | TP53 | P04637 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | GRM5 | P41594 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | KCNT1 | Q5JUK3 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.47 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30153356 | 1.00 | KDM4E (0.55) | KDM4ESMN1; SMN2MAPTTP53MEN1 | |
| SCHEMBL28399748 | 0.88 | LMNA (0.62) | MAPTMEN1KMT2AGAALMNA | |
| SCHEMBL28393670 | 0.87 | KCNK3 (0.56) | KDM4ESMN1; SMN2MAPTTP53MEN1 | |
| SCHEMBL30153256 | 0.87 | KCNK3 (0.56) | KDM4ESMN1; SMN2MAPTTP53MEN1 | |
| SCHEMBL28407306 | 0.87 | POLB (0.52) | MAPTGRM5GAALMNAALDH1A1 | |
| SCHEMBL30153390 | 0.86 | GRM5 (0.49) | SMN1; SMN2GRM5GAALMNACYP2C19 | |
| SCHEMBL28401450 | 0.86 | GRM5 (0.49) | SMN1; SMN2GRM5GAALMNACYP2C19 | |
| SCHEMBL28399448 | 0.85 | STIM1 (0.49) | SMN1; SMN2MEN1KMT2AGRM5LMNA | |
| SCHEMBL28401209 | 0.84 | SMN1; SMN2 (0.58) | KDM4ESMN1; SMN2MAPTTP53MEN1 | |
| SCHEMBL30153252 | 0.84 | SMN1; SMN2 (0.58) | KDM4ESMN1; SMN2MAPTTP53MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111187215-B | Fluorine-containing pyrazole amide derivative, preparation method and application thereof | 西北农林科技大学 | 2023-02-24 | — | — | CN | disclosed |
| CN-111187215-A | Fluorine-containing pyrazole amide derivative, preparation method and application thereof | 西北农林科技大学 | 2020-05-22 | — | — | CN | disclosed |