Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | LDHA | P00338 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | DHODH | Q02127 | 2/20 | 0.44 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.44 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.44 |
| ▸ | XDH | P47989 | 1/20 | 0.43 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.43 |
| ▸ | MYC | P01106 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.39 |
| ▸ | TMIGD3 | P0DMS9 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2996263 | 0.74 | HDAC6 (0.41) | HDAC6 | |
| SCHEMBL6489509 | 0.73 | L3MBTL1 (0.56) | HDAC6L3MBTL1XDHSLC22A12MYC | |
| SCHEMBL28973247 | 0.73 | L3MBTL1 (0.46) | HDAC6L3MBTL1KDM4EALDH1A1TSHR | |
| SCHEMBL18766658 | 0.71 | BRD4 (0.47) | HDAC6 | |
| SCHEMBL1419899 | 0.71 | KDM4E (0.50) | L3MBTL1DHODHXDHSLC22A12MYC | |
| SCHEMBL15743470 | 0.70 | L3MBTL1 (0.49) | HDAC6L3MBTL1 | |
| SCHEMBL23012585 | 0.70 | L3MBTL1 (0.44) | HDAC6L3MBTL1XDHSLC22A12KDM4E | |
| Hydrochloric Acid SCHEMBL9091092 | 0.70 | DHODH (0.49) | L3MBTL1DHODHXDHSLC22A12MYC | |
| Lithium SCHEMBL31115344 | 0.70 | DHODH (0.49) | L3MBTL1DHODHXDHSLC22A12MYC | |
| SCHEMBL269897 | 0.70 | MCL1 (0.57) | LDHAMYCKDM4EUSP2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111187262-A | Imidazo [1,2-a ] pyridine derivative and preparation method and application thereof | 沈阳药科大学 | 2020-05-22 | — | — | CN | disclosed |