SCHEMBL28401558

SCHEMBL28401558

Cc1ccc(C(=O)CC(=O)NS(=O)(=O)c2ccccc2C)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 3/20 0.54
NPC1 O15118 2/20 0.54
MEN1 O00255 1/20 0.54
KMT2A Q03164 1/20 0.54
CA1 P00915 3/20 0.48
CA2 P00918 3/20 0.48
CA9 Q16790 3/20 0.48
HSD11B1 P28845 1/20 0.47
MAPT P10636 1/20 0.46
RAPGEF3 O95398 1/20 0.45
ALKBH2 Q6NS38 1/20 0.45
ALKBH3 Q96Q83 1/20 0.45
CA12 O43570 1/20 0.43
RECQL P46063 1/20 0.43
ITGAV P06756 1/20 0.43
BCAT1 P54687 1/20 0.43
SLC1A3 P43003 1/20 0.42
SLC1A2 P43004 1/20 0.42
SLC1A1 P43005 1/20 0.42
AKR1C3 P42330 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9178001 0.83 CA1 (0.58) RAB9ANPC1CA1CA2CA9
SCHEMBL28398115 0.80 CA1 (0.49) CA1CA2CA9RAPGEF3ALKBH2
SCHEMBL28396566 0.80 EGFR (0.57) RAB9ANPC1MEN1KMT2ACA1
SCHEMBL28396585 0.79 MEN1 (0.62) RAB9ANPC1MEN1KMT2AHSD11B1
SCHEMBL27367514 0.78 CA1 (0.50) KMT2ACA1CA2CA9MAPT
SCHEMBL6279917 0.76 SLC1A3 (0.50) CA1CA2CA9ALKBH2ALKBH3
SCHEMBL10985683 0.76 CA1 (0.46) CA1CA2CA9RAPGEF3ALKBH2
SCHEMBL3206422 0.76 SLC1A3 (0.55) CA1CA2CA9ALKBH2ALKBH3
SCHEMBL3977341 0.75 CA1 (0.48) CA1CA2CA9CA12AKR1C3
SCHEMBL3548718 0.74 CA1 (0.52) CA1CA2CA9ALKBH2ALKBH3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111187184-B Novel method for synthesizing sulfonyl ketoamide 盐城工学院 2022-04-08 CN disclosed
CN-111187184-A Novel method for synthesizing sulfonyl ketoamide 盐城工学院 2020-05-22 CN disclosed