Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 5/20 | 0.46 |
| ▸ | CA2 | P00918 | 5/20 | 0.46 |
| ▸ | CA9 | Q16790 | 5/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.45 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.45 |
| ▸ | CA12 | O43570 | 3/20 | 0.45 |
| ▸ | ALKBH2 | Q6NS38 | 1/20 | 0.44 |
| ▸ | ALKBH3 | Q96Q83 | 1/20 | 0.44 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.43 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.43 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.43 |
| ▸ | FBP1 | P09467 | 1/20 | 0.43 |
| ▸ | MMP1 | P03956 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
| ▸ | MMP8 | P22894 | 1/20 | 0.43 |
| ▸ | MMP13 | P45452 | 1/20 | 0.43 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.43 |
| ▸ | ITGAV | P06756 | 1/20 | 0.42 |
| ▸ | RAPGEF3 | O95398 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27367514 | 0.87 | CA1 (0.50) | CA1CA2CA9AKR1C3AKR1C2 | |
| SCHEMBL6279917 | 0.84 | SLC1A3 (0.50) | CA1CA2CA9CA12ALKBH2 | |
| SCHEMBL28398115 | 0.82 | CA1 (0.49) | CA1CA2CA9CA12ALKBH2 | |
| SCHEMBL10994007 | 0.82 | CA1 (0.47) | CA1CA2CA9AKR1C3AKR1C2 | |
| SCHEMBL10990669 | 0.80 | CA1 (0.42) | CA1CA2CA9AKR1C3AKR1C2 | |
| SCHEMBL3206422 | 0.78 | SLC1A3 (0.55) | CA1CA2CA9CA12ALKBH2 | |
| SCHEMBL3548718 | 0.76 | CA1 (0.52) | CA1CA2CA9CA12ALKBH2 | |
| SCHEMBL28401558 | 0.76 | RAB9A (0.54) | CA1CA2CA9AKR1C3AKR1C2 | |
| SCHEMBL9176782 | 0.76 | FLT1 (0.63) | CA1CA2CA9ALKBH2ALKBH3 | |
| SCHEMBL3548714 | 0.75 | CA1 (0.51) | CA1CA2CA9CA12ALKBH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4495365-A | N-Acylsulfonamide herbicidal antidotes | STAUFFER CHEMICAL CO. (US) | 1985-01-22 | — | — | US | disclosed |
| US-4347380-A | N-Acylsulfonamide herbicidal antidotes | STAUFFER CHEMICAL COMPANY (US) | 1982-08-31 | — | — | US | disclosed |