Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.69 |
| ▸ | ACE | P12821 | 4/20 | 0.67 |
| ▸ | POLB | P06746 | 3/20 | 0.65 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.65 |
| ▸ | TP53 | P04637 | 1/20 | 0.65 |
| ▸ | ITGB2 | P05107 | 2/20 | 0.65 |
| ▸ | ICAM1 | P05362 | 2/20 | 0.65 |
| ▸ | ITGAL | P20701 | 2/20 | 0.65 |
| ▸ | MEN1 | O00255 | 3/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.62 |
| ▸ | ECE1 | P42892 | 3/20 | 0.62 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.62 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28401650 | 1.00 | ALOX15 (0.69) | ALOX15ACEPOLBP2RY14TP53 | |
| SCHEMBL11382213 | 0.99 | ALOX15 (0.70) | ALOX15ACEPOLBP2RY14TP53 | |
| SCHEMBL11382215 | 0.99 | ALOX15 (0.70) | ALOX15ACEPOLBP2RY14TP53 | |
| SCHEMBL15692400 | 0.94 | ACE (0.70) | ALOX15ACEKDM4EECE1 | |
| SCHEMBL28396919 | 0.93 | MEN1 (0.64) | ALOX15ACEPOLBP2RY14TP53 | |
| SCHEMBL28396920 | 0.93 | MEN1 (0.64) | ALOX15ACEPOLBP2RY14TP53 | |
| SCHEMBL31036188 | 0.93 | MEN1 (0.66) | ALOX15ACEPOLBP2RY14TP53 | |
| SCHEMBL21001415 | 0.93 | MEN1 (0.66) | ALOX15ACEPOLBP2RY14TP53 | |
| SCHEMBL21001416 | 0.93 | MEN1 (0.66) | ALOX15ACEPOLBP2RY14TP53 | |
| SCHEMBL31036095 | 0.93 | MEN1 (0.66) | ALOX15ACEPOLBP2RY14TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111132962-B | Tryptophan derivative and application thereof | 彭险峰 | 2023-09-08 | — | — | CN | claimed |
| CN-111132962-A | Tryptophan derivative and application thereof | 黄华成 | 2020-05-08 | — | — | CN | claimed |
| CN-111132962-B | Tryptophan derivative and application thereof | 彭险峰 | 2023-09-08 | — | — | CN | disclosed |
| CN-111132962-A | Tryptophan derivative and application thereof | 黄华成 | 2020-05-08 | — | — | CN | disclosed |