Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | CRACR2A | Q9BSW2 | 3/20 | 0.54 |
| ▸ | TP53 | P04637 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | DHODH | Q02127 | 1/20 | 0.46 |
| ▸ | TYK2 | P29597 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | ADCY8 | P40145 | 1/20 | 0.44 |
| ▸ | ADCY1 | Q08828 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28397911 | 0.87 | KMT2A (0.52) | CRACR2AKMT2AHPGDPOLBRECQL | |
| SCHEMBL28397884 | 0.87 | RECQL (0.60) | TP53RXFP1RAB9ARECQLALDH1A1 | |
| SCHEMBL29047734 | 0.86 | RXFP1 (0.46) | MAPTCRACR2ATP53KMT2ARXFP1 | |
| SCHEMBL30546957 | 0.86 | RXFP1 (0.46) | MAPTCRACR2ATP53KMT2ARXFP1 | |
| SCHEMBL28398111 | 0.86 | STIM1 (0.53) | KMT2ARXFP1HPGDNPC1RAB9A | |
| SCHEMBL28398322 | 0.84 | MAPT (0.59) | MAPTTP53KMT2ARXFP1NPC1 | |
| SCHEMBL28407306 | 0.82 | POLB (0.52) | MAPTNPC1RAB9APOLBALDH1A1 | |
| SCHEMBL13056023 | 0.82 | MAPT (0.47) | MAPTTP53KMT2AHPGDNPC1 | |
| SCHEMBL29047658 | 0.82 | RXFP1 (0.57) | MAPTCRACR2AKMT2ARXFP1SMN1; SMN2 | |
| SCHEMBL30546927 | 0.82 | RXFP1 (0.57) | MAPTCRACR2AKMT2ARXFP1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111187215-B | Fluorine-containing pyrazole amide derivative, preparation method and application thereof | 西北农林科技大学 | 2023-02-24 | — | — | CN | disclosed |
| CN-111187215-A | Fluorine-containing pyrazole amide derivative, preparation method and application thereof | 西北农林科技大学 | 2020-05-22 | — | — | CN | disclosed |