Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | KCNK3 | O14649 | 3/20 | 0.49 |
| ▸ | KCNK9 | Q9NPC2 | 3/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.49 |
| ▸ | F2R | P25116 | 1/20 | 0.47 |
| ▸ | PTPRC | P08575 | 1/20 | 0.46 |
| ▸ | PTGES | O14684 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29047633 | 0.88 | RECQL (0.48) | RECQLLMNATP53RXFP1HDAC3 | |
| SCHEMBL30546929 | 0.88 | RECQL (0.48) | RECQLLMNATP53RXFP1HDAC3 | |
| SCHEMBL28402002 | 0.87 | MAPT (0.55) | RECQLTP53RXFP1ALDH1A1RAB9A | |
| SCHEMBL28397911 | 0.87 | KMT2A (0.52) | RECQLLMNAGAAKDM4EALDH1A1 | |
| SCHEMBL28398111 | 0.86 | STIM1 (0.53) | LMNARXFP1KDM4EALDH1A1RAB9A | |
| SCHEMBL28398322 | 0.84 | MAPT (0.59) | GAAKCNK3KCNK9TP53RXFP1 | |
| SCHEMBL28393654 | 0.84 | RECQL (0.57) | RECQLLMNAGAAKCNK3KCNK9 | |
| SCHEMBL28407306 | 0.82 | POLB (0.52) | LMNAGAAKCNK3ALDH1A1RAB9A | |
| SCHEMBL13056023 | 0.82 | MAPT (0.47) | RECQLLMNAKCNK3KCNK9PTGS1 | |
| SCHEMBL29047658 | 0.82 | RXFP1 (0.57) | RXFP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111187215-B | Fluorine-containing pyrazole amide derivative, preparation method and application thereof | 西北农林科技大学 | 2023-02-24 | — | — | CN | disclosed |
| CN-111187215-A | Fluorine-containing pyrazole amide derivative, preparation method and application thereof | 西北农林科技大学 | 2020-05-22 | — | — | CN | disclosed |