Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.32 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.31 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.31 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23431347 | 0.81 | NPSR1 (0.44) | NPSR1TDP1ALDH1A1L3MBTL1ATM | |
| SCHEMBL12792202 | 0.78 | KDM4E (0.32) | NPSR1TDP1L3MBTL1MAPK1ATM | |
| SCHEMBL12792049 | 0.75 | NPSR1 (0.40) | NPSR1TDP1ALDH1A1L3MBTL1HPGD | |
| SCHEMBL16447094 | 0.72 | NPSR1 (0.42) | NPSR1TDP1HSD17B10ALDH1A1L3MBTL1 | |
| SCHEMBL801127 | 0.72 | NPSR1 (0.40) | NPSR1TDP1TSHRALDH1A1L3MBTL1 | |
| SCHEMBL14973337 | 0.71 | HSD17B10 (0.39) | TDP1TSHRHSD17B10ALDH1A1CYP2A6 | |
| SCHEMBL12792062 | 0.71 | NPSR1 (0.40) | NPSR1TSHRALDH1A1L3MBTL1HPGD | |
| SCHEMBL23911727 | 0.71 | KDM4E (0.46) | NPSR1ALDH1A1L3MBTL1HPGDATM | |
| SCHEMBL28889116 | 0.69 | NR4A2 (0.41) | LDHA | |
| SCHEMBL12792053 | 0.69 | KDM4E (0.47) | NPSR1TSHRHSD17B10ALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111206262-B | Synthesis method of N-phosphino-substituted carbazole and indole derivatives | 新疆大学 | 2021-12-07 | — | — | CN | disclosed |
| CN-111206262-A | Synthesis method of N-phosphino-substituted carbazole and indole derivatives | 新疆大学 | 2020-05-29 | — | — | CN | disclosed |