Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | HPRT1 | P00492 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.36 |
| ▸ | TYMS | P04818 | 2/20 | 0.36 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.35 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19545508 | 0.74 | ALDH1A1 (0.48) | HSD17B10ALDH1A1TSHRTDP1CYP2A6 | |
| SCHEMBL28402349 | 0.71 | NPSR1 (0.36) | HSD17B10ALDH1A1TSHRTDP1CYP2A6 | |
| SCHEMBL31532798 | 0.70 | TLR8 (0.40) | HSD17B10ALDH1A1TSHRTDP1CYP2A6 | |
| SCHEMBL30772964 | 0.70 | GPR3 (0.52) | HSD17B10ALDH1A1TSHRTDP1CYP2A6 | |
| SCHEMBL19831358 | 0.70 | HSD17B10 (0.48) | HSD17B10ALDH1A1TSHRTDP1CYP2A6 | |
| SCHEMBL10023491 | 0.70 | GPR3 (0.52) | HSD17B10ALDH1A1TSHRTDP1CYP2A6 | |
| SCHEMBL13086954 | 0.67 | ATM (0.56) | HSD17B10ALDH1A1TSHRTDP1CYP2A6 | |
| SCHEMBL17127066 | 0.67 | HSD17B10 (0.44) | HSD17B10ALDH1A1TSHRTDP1CYP2A6 | |
| SCHEMBL31532757 | 0.67 | TLR8 (0.47) | TDP1 | |
| SCHEMBL24427107 | 0.67 | TLR8 (0.47) | HSD17B10ALDH1A1TSHRTDP1CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130137889-A1 | STRECKER REAGENTS, THEIR DERIVATIVES, METHODS FOR FORMING THE SAME AND IMPROVED STRECKER REACTION | NANJING UNIVERSITY (CN) | 2013-05-30 | — | — | US | claimed |
| US-20130137889-A1 | STRECKER REAGENTS, THEIR DERIVATIVES, METHODS FOR FORMING THE SAME AND IMPROVED STRECKER REACTION | NANJING UNIVERSITY (CN) | 2013-05-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130137889-A1 | STRECKER REAGENTS, THEIR DERIVATIVES, METHODS FOR FORMING THE SAME AND IMPROVED STRECKER REACTION | PHOSPHO1, AGL, ITPA | HSD17B10 2149/4885ALDH1A1 2548/4885TSHR 2881/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.