SCHEMBL28403102

SCHEMBL28403102

CCCc1ccc(C(=O)OC(=O)c2ccc(CCC)c(C)c2)cc1C

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 2/20 0.41
CA1 P00915 2/20 0.41
CA2 P00918 2/20 0.41
CA7 P43166 2/20 0.41
CA9 Q16790 2/20 0.41
CA14 Q9ULX7 2/20 0.41
PPARG P37231 5/20 0.40
PPARA Q07869 5/20 0.40
ESR1 P03372 3/20 0.38
MGLL Q99685 1/20 0.38
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
ATM Q13315 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
HSD17B2 P37059 1/20 0.37
ESR2 Q92731 1/20 0.37
PRKCI P41743 1/20 0.37
GRM1 Q13255 1/20 0.36
LMNA P02545 1/20 0.36
CYP1A2 P05177 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28681735 0.92 LMNA (0.45) PPARGPPARAMEN1KMT2ALMNA
SCHEMBL28407101 0.90 ESR1 (0.43) CA12CA1CA2CA7CA9
SCHEMBL13553385 0.88 PPARG (0.51) CA12CA1CA2CA7CA9
SCHEMBL28401900 0.87 CA12 (0.44) CA12CA1CA2CA7CA9
SCHEMBL28403107 0.86 PPARG (0.44) CA12CA1CA2CA7CA9
SCHEMBL28398118 0.84 PPARG (0.46) CA12CA1CA2CA7CA9
SCHEMBL28399314 0.84 PPARG (0.43) CA12CA1CA2CA7CA9
SCHEMBL28675288 0.84 LMNA (0.43) PPARGPPARAESR1MGLLMEN1
SCHEMBL16769472 0.82 PRKCI (0.46) CA12KMT2AL3MBTL1PRKCILMNA
SCHEMBL15905718 0.82 EPHX2 (0.50) ESR1MEN1KMT2AGRM1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111234070-B Catalyst component, catalyst system and prepolymerized catalyst for olefin polymerization, use thereof and olefin polymerization process 中国石油化工股份有限公司 2022-03-01 CN claimed
CN-111234073-B Catalyst component, catalyst system and prepolymerized catalyst for olefin polymerization, use thereof and olefin polymerization process 中国石油化工股份有限公司 2021-12-31 CN claimed
CN-111234073-A Catalyst component, catalyst system and prepolymerized catalyst for olefin polymerization, use thereof and olefin polymerization process 中国石油化工股份有限公司 2020-06-05 CN claimed
CN-111234070-A Catalyst component, catalyst system and prepolymerized catalyst for olefin polymerization, use thereof and olefin polymerization process 中国石油化工股份有限公司 2020-06-05 CN claimed
CN-111234070-B Catalyst component, catalyst system and prepolymerized catalyst for olefin polymerization, use thereof and olefin polymerization process 中国石油化工股份有限公司 2022-03-01 CN disclosed
CN-111234073-B Catalyst component, catalyst system and prepolymerized catalyst for olefin polymerization, use thereof and olefin polymerization process 中国石油化工股份有限公司 2021-12-31 CN disclosed
CN-111234073-A Catalyst component, catalyst system and prepolymerized catalyst for olefin polymerization, use thereof and olefin polymerization process 中国石油化工股份有限公司 2020-06-05 CN disclosed
CN-111234070-A Catalyst component, catalyst system and prepolymerized catalyst for olefin polymerization, use thereof and olefin polymerization process 中国石油化工股份有限公司 2020-06-05 CN disclosed