Methyl 3-Phenylpropanoate

Methyl 3-Phenylpropanoate

SCHEMBL28403153

COC(=O)CCc1ccccc1.COC(=O)Cc1ccccc1C

nearest known ligand 0.57

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.57
TDP1 Q9NUW8 3/20 0.50
CA12 O43570 1/20 0.49
CA7 P43166 1/20 0.49
CA9 Q16790 1/20 0.49
CA14 Q9ULX7 1/20 0.49
LMNA P02545 2/20 0.49
KDM4E B2RXH2 1/20 0.49
P2RX7 Q99572 1/20 0.47
HTT P42858 1/20 0.46
L3MBTL1 Q9Y468 2/20 0.46
RECQL P46063 1/20 0.46
POLB P06746 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.44
CTBP2 P56545 1/20 0.44
CYP11B1 P15538 1/20 0.44
CYP11B2 P19099 1/20 0.44
CYP4F2 P78329 1/20 0.44
CYP4A11 Q02928 1/20 0.44
TAAR1 Q96RJ0 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL265432 0.86 CTBP2 (0.51) ALDH1A1LMNAKDM4EHTTL3MBTL1
SCHEMBL30522283 0.86 CTBP2 (0.51) ALDH1A1LMNAKDM4EHTTL3MBTL1
Water SCHEMBL27319077 0.84 CTBP2 (0.50) ALDH1A1LMNAKDM4EHTTL3MBTL1
Methyl 3-Phenylpropanoate SCHEMBL168711 0.84 TDP1 (0.68) ALDH1A1TDP1CA12CA7CA9
SCHEMBL8914213 0.82 CYP4F2 (0.51) ALDH1A1TDP1LMNAKDM4EHTT
Methyl 3-Phenylpropanoate SCHEMBL1893702 0.82 TDP1 (0.66) ALDH1A1TDP1CA12CA7CA9
Methyl 3-Phenylpropanoate SCHEMBL27447160 0.82 TDP1 (0.66) ALDH1A1TDP1CA12CA7CA9
Methyl 3-Phenylpropanoate SCHEMBL27315471 0.82 TDP1 (0.66) ALDH1A1TDP1CA12CA7CA9
SCHEMBL28410864 0.82 TSHR (0.59) ALDH1A1TDP1LMNAP2RX7HTT
Methyl 3-Phenylpropanoate SCHEMBL27822992 0.81 TDP1 (0.59) ALDH1A1TDP1CA12CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111087306-B Method for preparing organic carboxylic ester by aryl bidentate phosphine ligand combined catalysis 南京诚志清洁能源有限公司 2021-08-03 CN disclosed
CN-111087306-A Method for preparing organic carboxylic ester by aryl bidentate phosphine ligand combined catalysis 南京诚志清洁能源有限公司 2020-05-01 CN disclosed