SCHEMBL28403160

SCHEMBL28403160

CC=C(N)Cc1cc(F)c(F)cc1F

nearest known ligand 0.41

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 9/20 0.41
HDAC1 Q13547 1/20 0.32
HDAC8 Q9BY41 1/20 0.32
RORC P51449 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28400680 1.00 DPP4 (0.41) DPP4HDAC1HDAC8RORC
SCHEMBL22484240 1.00 DPP4 (0.41) DPP4HDAC1HDAC8RORC
SCHEMBL30515475 0.82 DPP4 (0.38) DPP4
SCHEMBL13780810 0.80 DPP4 (0.36) DPP4HDAC1HDAC8RORC
SCHEMBL749410 0.77 HDAC1 (0.35) DPP4HDAC1HDAC8RORC
SCHEMBL749409 0.77 HDAC1 (0.35) DPP4HDAC1HDAC8RORC
SCHEMBL30136575 0.77 HDAC1 (0.35) DPP4HDAC1HDAC8RORC
SCHEMBL749408 0.77 HDAC1 (0.35) DPP4HDAC1HDAC8RORC
SCHEMBL2861837 0.76 DPP4 (0.41) DPP4HDAC1HDAC8RORC
SCHEMBL742800 0.76 DPP4 (0.41) DPP4HDAC1HDAC8RORC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111204094-A TPEE acoustic film and production method thereof 苏州市新广益电子有限公司 2020-05-29 CN disclosed